Expression of SCARA3 in cancer - Summary - The Human Protein Atlas

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SCARA3

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Scavenger receptor class A, member 3

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA047386

GENE INFORMATION
Gene name	SCARA3 (HGNC Symbol)
Synonyms	APC7, CSR, CSR1, MSLR1, MSRL1
Description	Scavenger receptor class A, member 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	p21.1
Chromosome location (bp)	27633868 - 27676776
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168077 (version 83.38)
Entrez gene	51435
UniProt	Q6AZY7 (UniProt - Evidence at protein level)
neXtProt	NX_Q6AZY7
Antibodypedia	SCARA3 antibodies

PROTEIN BROWSER

SCARA3-001	SCARA3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SCARA3-001 ENSP00000301904 ENST00000301904	Q6AZY7 [Direct mapping] Scavenger receptor class A member 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005044 [scavenger receptor activity] GO:0005515 [protein binding] GO:0005581 [collagen trimer] GO:0005789 [endoplasmic reticulum membrane] GO:0006898 [receptor-mediated endocytosis] GO:0006979 [response to oxidative stress] GO:0009650 [UV protection] GO:0016021 [integral component of membrane] Show all	606 aa 65.1 kDa	No	1
SCARA3-002 ENSP00000337985 ENST00000337221	Q6AZY7 [Direct mapping] Scavenger receptor class A member 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005044 [scavenger receptor activity] GO:0005515 [protein binding] GO:0005581 [collagen trimer] GO:0005789 [endoplasmic reticulum membrane] GO:0006898 [receptor-mediated endocytosis] GO:0006979 [response to oxidative stress] GO:0009650 [UV protection] GO:0016021 [integral component of membrane] Show all	466 aa 52.4 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.