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SCARA3

GENERAL INFORMATION

Gene name

 SCARA3

Gene description

 Scavenger receptor class A, member 3

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (fallopian tube)
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA047386
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (fallopian tube)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 SCARA3 (HGNC Symbol)

Synonyms

 APC7, CSR, CSR1, MSLR1, MSRL1

Description

 Scavenger receptor class A, member 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete reactive oxygen species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 8

Cytoband

 p21.1

Chromosome location (bp)

 27633868 - 27676776

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168077 (version 83.38)

Entrez gene

 51435

UniProt

 Q6AZY7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6AZY7

Antibodypedia

 SCARA3 antibodies

PROTEIN BROWSER
SCARA3-001
SCARA3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCARA3-001
ENSP00000301904
ENST00000301904
Q6AZY7 [Direct mapping]
Scavenger receptor class A member 3
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005044 [scavenger receptor activity]
GO:0005515 [protein binding]
GO:0005581 [collagen trimer]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006898 [receptor-mediated endocytosis]
GO:0006979 [response to oxidative stress]
GO:0009650 [UV protection]
GO:0016021 [integral component of membrane]
Show all
 606 aa
65.1 kDa 		No 1
SCARA3-002
ENSP00000337985
ENST00000337221
Q6AZY7 [Direct mapping]
Scavenger receptor class A member 3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005044 [scavenger receptor activity]
GO:0005515 [protein binding]
GO:0005581 [collagen trimer]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006898 [receptor-mediated endocytosis]
GO:0006979 [response to oxidative stress]
GO:0009650 [UV protection]
GO:0016021 [integral component of membrane]
Show all
 466 aa
52.4 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.