Expression of COA6 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Cytochrome c oxidase assembly factor 6

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Endometrial cancer

STAINING SUMMARY

HPA028588

GENE INFORMATION
Gene name	COA6 (HGNC Symbol)
Synonyms	C1orf31
Description	Cytochrome c oxidase assembly factor 6 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the cytochrome c oxidase subunit 6B family. The encoded protein associates with cytochrome c oxidase may act has an cytochrome c oxidase mitochondrial respiratory complex VI assembly factor. Mutations in this gene may be associated with fatal infantile cardiomyopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Chromosome	1
Cytoband	q42.2
Chromosome location (bp)	234373456 - 234384049
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168275 (version 83.38)
Entrez gene	388753
UniProt	Q5JTJ3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5JTJ3
Antibodypedia	COA6 antibodies

PROTEIN BROWSER

COA6-001	COA6-002	COA6-003	COA6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COA6-001 ENSP00000355574 ENST00000366615	X6R5Z6 [Direct mapping] Cytochrome c oxidase assembly factor 6 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004129 [cytochrome-c oxidase activity] GO:0005739 [mitochondrion] GO:1902600 [hydrogen ion transmembrane transport] Show all	155 aa 18 kDa	No	0
COA6-002 ENSP00000355572 ENST00000366613	Q5JTJ3 [Direct mapping] Cytochrome c oxidase assembly factor 6 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004129 [cytochrome-c oxidase activity] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0044822 [poly(A) RNA binding] GO:1902600 [hydrogen ion transmembrane transport] Show all	125 aa 14.1 kDa	No	0
COA6-003 ENSP00000355571 ENST00000366612	Q5JTJ3 [Direct mapping] Cytochrome c oxidase assembly factor 6 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004129 [cytochrome-c oxidase activity] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0044822 [poly(A) RNA binding] GO:1902600 [hydrogen ion transmembrane transport] Show all	79 aa 9.4 kDa	No	0
COA6-201 ENSP00000479686 ENST00000619305	Q5JTJ3 [Direct mapping] Cytochrome c oxidase assembly factor 6 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004129 [cytochrome-c oxidase activity] GO:0005739 [mitochondrion] GO:0008150 [biological_process] GO:0044822 [poly(A) RNA binding] GO:1902600 [hydrogen ion transmembrane transport] Show all	79 aa 9.4 kDa	No	0