Expression of SDPR in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Serum deprivation response

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039325

GENE INFORMATION
Gene name	SDPR (HGNC Symbol)
Synonyms	cavin-2, CAVIN2, PS-p68, SDR
Description	Serum deprivation response (HGNC Symbol)
Entrez gene summary	This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]
Chromosome	2
Cytoband	q32.3
Chromosome location (bp)	191834302 - 191847255
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168497 (version 83.38)
Entrez gene	8436
UniProt	O95810 (UniProt - Evidence at protein level)
neXtProt	NX_O95810
Antibodypedia	SDPR antibodies

PROTEIN BROWSER

SDPR-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SDPR-001 ENSP00000305675 ENST00000304141	O95810 [Direct mapping] Serum deprivation-response protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001786 [phosphatidylserine binding] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005543 [phospholipid binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005901 [caveola] GO:0045121 [membrane raft] Show all	425 aa 47.2 kDa	No	0