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Several colorectal and prostate cancers as well as a few cases of gastric, pancreatic and liver cancers showed weak to moderate membranous and/or cytoplasmic positivity. Remaining malignancies were generally negative.
GENE INFORMATION
Gene name
VAMP5
Synonyms
Description
Vesicle-associated membrane protein 5 (HGNC Symbol)
Entrez gene summary
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008]