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Most cancers showed moderate cytoplasmic positivity. Several hepatocellular carcinomas, endometrial, ovarian and colorectal cancers were strongly stained. Lymphomas were weakly stained or negative in several cases.
Cancer tissues showed weak to moderate immunoreactivity. Several cases of renal, gastric and hepatocellular carcinomas were negative.
GENE INFORMATION
Gene name
LUZP1 (HGNC Symbol)
Synonyms
LUZP
Description
Leucine zipper protein 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
