Cell atlas - LUZP1 - The Human Protein Atlas

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LUZP1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Actin filaments
	Cytosol
	Vesicles

Human cell
	Actin Filaments
	Cytosol
	Vesicles

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GENERAL INFORMATION
Gene name	LUZP1
Gene description	Leucine zipper protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the actin filaments. In addition localized to the cytosol & vesicles.
RNA cell category	Cell line enhanced (TIME)
Protein evidence	Evidence at protein level
Main location	Localized to the Actin filaments (uncertain)
Additional location	In addition localized to the Vesicles (uncertain), Cytosol (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 2 antibodies. HPA028506 , HPA028542
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (TIME) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the actin filaments. In addition localized to the cytosol & vesicles.

Main location

Actin filaments (uncertain)

Additional location

Vesicles (uncertain), Cytosol (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA028506	A-431	Actin filaments
HPA028506	A-431	Cytosol
HPA028506	U-2 OS	Actin filaments
HPA028506	U-2 OS	Cytosol
HPA028506	U-251 MG	Actin filaments
HPA028506	U-251 MG	Cytosol
HPA028542	A-431	Vesicles
HPA028542	A-431	Actin filaments
HPA028542	U-2 OS	Vesicles
HPA028542	U-2 OS	Actin filaments
HPA028542	U-251 MG	Vesicles
HPA028542	U-251 MG	Actin filaments

GENE INFORMATION
Gene name	LUZP1 (HGNC Symbol)
Synonyms	LUZP
Description	Leucine zipper protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains a leucine zipper motif. The exact function of the encoded protein is not known. In mice this gene affects neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Chromosome	1
Cytoband	p36.12
Chromosome location (bp)	23084023 - 23177808
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169641 (version 83.38)
Entrez gene	7798
UniProt	Q86V48 (UniProt - Evidence at protein level)
neXtProt	NX_Q86V48
Antibodypedia	LUZP1 antibodies

PROTEIN BROWSER

LUZP1-001	LUZP1-002	LUZP1-003	LUZP1-004	LUZP1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LUZP1-001 ENSP00000313705 ENST00000314174	Q86V48 [Direct mapping] Leucine zipper protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0016020 [membrane] GO:0070062 [extracellular exosome] Show all	1026 aa 114.6 kDa	No	0
LUZP1-002 ENSP00000303758 ENST00000302291	Q86V48 [Direct mapping] Leucine zipper protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003281 [ventricular septum development] GO:0005634 [nucleus] GO:0016020 [membrane] GO:0021503 [neural fold bending] GO:0060840 [artery development] GO:0070062 [extracellular exosome] Show all	1076 aa 120.3 kDa	No	0
LUZP1-003 ENSP00000428061 ENST00000471849	E5RFK8 [Direct mapping] Leucine zipper protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		273 aa 32.1 kDa	No	0
LUZP1-004 ENSP00000429657 ENST00000475164	E5RHU7 [Direct mapping] Leucine zipper protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		35 aa 4.2 kDa	No	0
LUZP1-201 ENSP00000393460 ENST00000418342	Q86V48 [Direct mapping] Leucine zipper protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0016020 [membrane] GO:0070062 [extracellular exosome] Show all	1076 aa 120.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.