Cell atlas - UGP2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

UGP2

premium

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Mitochondria
	Nucleoplasm

Human cell
	Centrosome
	Mitochondria
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	UGP2
Gene description	UDP-glucose pyrophosphorylase 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	15
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria & centrosome. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Centrosome (approved), Mitochondria (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA064836
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria & centrosome. In addition localized to the nucleoplasm.

Main location

Centrosome (approved), Mitochondria (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA064836	A-431	Nucleoplasm
	HPA064836	A-431	Mitochondria
	HPA064836	RH-30	Centrosome
	HPA064836	RH-30	Mitochondria
	HPA064836	U-2 OS	Centrosome
	HPA064836	U-2 OS	Mitochondria

GENE INFORMATION
Gene name	UGP2 (HGNC Symbol)
Synonyms	UGP1, UGPP1
Description	UDP-glucose pyrophosphorylase 2 (HGNC Symbol)
Entrez gene summary	The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	p15
Chromosome location (bp)	63840940 - 63891562
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169764 (version 83.38)
Entrez gene	7360
UniProt	Q16851 (UniProt - Evidence at protein level)
neXtProt	NX_Q16851
Antibodypedia	UGP2 antibodies

PROTEIN BROWSER

UGP2-001	UGP2-002	UGP2-004	UGP2-005	UGP2-009	UGP2-011	UGP2-012	UGP2-021	UGP2-023	UGP2-025	UGP2-029	UGP2-030	UGP2-201	UGP2-202	UGP2-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UGP2-001 ENSP00000338703 ENST00000337130	Q16851 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003983 [UTP:glucose-1-phosphate uridylyltransferase activity] GO:0005515 [protein binding] GO:0005536 [glucose binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0006006 [glucose metabolic process] GO:0006011 [UDP-glucose metabolic process] GO:0006065 [UDP-glucuronate biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0019255 [glucose 1-phosphate metabolic process] GO:0032557 [pyrimidine ribonucleotide binding] GO:0042802 [identical protein binding] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0052695 [cellular glucuronidation] GO:0070062 [extracellular exosome] GO:0070569 [uridylyltransferase activity] Show all	508 aa 56.9 kDa	No	0
UGP2-002 ENSP00000377939 ENST00000394417	Q16851 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003983 [UTP:glucose-1-phosphate uridylyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0006006 [glucose metabolic process] GO:0006011 [UDP-glucose metabolic process] GO:0006065 [UDP-glucuronate biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0042802 [identical protein binding] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0052695 [cellular glucuronidation] GO:0070062 [extracellular exosome] GO:0070569 [uridylyltransferase activity] Show all	497 aa 55.7 kDa	No	0
UGP2-004 ENSP00000411803 ENST00000445915	E7EUC7 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003983 [UTP:glucose-1-phosphate uridylyltransferase activity] GO:0006011 [UDP-glucose metabolic process] GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	517 aa 57.8 kDa	No	0
UGP2-005 ENSP00000420793 ENST00000467648	Q16851 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003983 [UTP:glucose-1-phosphate uridylyltransferase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0006006 [glucose metabolic process] GO:0006011 [UDP-glucose metabolic process] GO:0006065 [UDP-glucuronate biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0042802 [identical protein binding] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0052695 [cellular glucuronidation] GO:0070062 [extracellular exosome] GO:0070569 [uridylyltransferase activity] Show all	497 aa 55.7 kDa	No	0
UGP2-009 ENSP00000418375 ENST00000484142	C9J6Q0 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		49 aa 5.6 kDa	No	0
UGP2-011 ENSP00000419548 ENST00000482668	C9JTZ5 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	105 aa 12 kDa	No	0
UGP2-012 ENSP00000417286 ENST00000480679	C9J3M0 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		38 aa 4.4 kDa	No	0
UGP2-021 ENSP00000419442 ENST00000488245	C9JUW1 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	135 aa 15.2 kDa	No	0
UGP2-023 ENSP00000419335 ENST00000475462	C9JVG3 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	171 aa 19.5 kDa	No	0
UGP2-025 ENSP00000420131 ENST00000497883	C9JQU9 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	175 aa 20 kDa	No	0
UGP2-029 ENSP00000420342 ENST00000491621	C9JNZ1 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	213 aa 24.3 kDa	No	0
UGP2-030 ENSP00000419238 ENST00000472047	C9JWG0 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	150 aa 16.9 kDa	No	0
UGP2-201 ENSP00000482043 ENST00000613823	A0A087WYS1 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003983 [UTP:glucose-1-phosphate uridylyltransferase activity] GO:0006011 [UDP-glucose metabolic process] GO:0008152 [metabolic process] GO:0070569 [uridylyltransferase activity] Show all	508 aa 57 kDa	No	0
UGP2-202 ENSP00000486332 ENST00000626380	F8WC70 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		52 aa 5.8 kDa	No	0
UGP2-203 ENSP00000486008 ENST00000627474	F2Z3P4 [Direct mapping] UTP--glucose-1-phosphate uridylyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		48 aa 5.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.