Cell atlas - NFRKB - The Human Protein Atlas

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NFRKB

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	NFRKB
Gene description	Nuclear factor related to kappaB binding protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (validated)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA007082 , HPA007128
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA007082	A-431	Nucleus
HPA007082	U-2 OS	Nucleus	Intensity
HPA007082	U-251 MG	Nucleus	Intensity
HPA007128	A-431	Nucleus
HPA007128	U-2 OS	Nucleus
HPA007128	U-251 MG	Nucleus

GENE INFORMATION
Gene name	NFRKB (HGNC Symbol)
Synonyms	DKFZp547B2013, INO80G
Description	Nuclear factor related to kappaB binding protein (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q24.3
Chromosome location (bp)	129863636 - 129895590
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170322 (version 83.38)
Entrez gene	4798
UniProt	Q6P4R8 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P4R8
Antibodypedia	NFRKB antibodies

PROTEIN BROWSER

NFRKB-001	NFRKB-002	NFRKB-003	NFRKB-004	NFRKB-005	NFRKB-006	NFRKB-007	NFRKB-009	NFRKB-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NFRKB-001 ENSP00000400476 ENST00000446488	Q6P4R8 [Direct mapping] Nuclear factor related to kappa-B-binding protein A0A024R3K9 [Target identity:100%; Query identity:100%] Nuclear factor related to kappaB binding protein, isoform CRA_c Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002020 [protease binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006281 [DNA repair] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006954 [inflammatory response] GO:0031011 [Ino80 complex] Show all	1299 aa 139 kDa	No	0
NFRKB-002 ENSP00000436926 ENST00000524794	Q6P4R8 [Direct mapping] Nuclear factor related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002020 [protease binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006281 [DNA repair] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006954 [inflammatory response] GO:0031011 [Ino80 complex] Show all	1324 aa 141.9 kDa	No	0
NFRKB-003 ENSP00000433572 ENST00000524746	Q6P4R8 [Direct mapping] Nuclear factor related to kappa-B-binding protein A0A024R3K9 [Target identity:100%; Query identity:100%] Nuclear factor related to kappaB binding protein, isoform CRA_c Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002020 [protease binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006281 [DNA repair] GO:0006310 [DNA recombination] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006954 [inflammatory response] GO:0031011 [Ino80 complex] Show all	1299 aa 139 kDa	No	0
NFRKB-004 ENSP00000432606 ENST00000531755	E9PQ59 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0031011 [Ino80 complex] Show all	987 aa 108.2 kDa	No	0
NFRKB-005 ENSP00000431854 ENST00000532225	E9PJG2 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0031011 [Ino80 complex] Show all	188 aa 21.9 kDa	No	0
NFRKB-006 ENSP00000431247 ENST00000526884	E9PM88 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0031011 [Ino80 complex] Show all	92 aa 10.4 kDa	No	0
NFRKB-007 ENSP00000434326 ENST00000529319	E9PJG2 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0031011 [Ino80 complex] Show all	188 aa 21.9 kDa	No	0
NFRKB-009 ENSP00000433764 ENST00000531318	E9PJE1 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		46 aa 5 kDa	No	0
NFRKB-010 ENSP00000432520 ENST00000526940	E9PQB0 [Direct mapping] Nuclear factor-related to kappa-B-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0031011 [Ino80 complex] Show all	122 aa 13.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.