Expression of FABP4 in cancer - Summary

CANCER ATLAS

Gene description

Fatty acid binding protein 4, adipocyte

Protein class

Cancer-related genes, Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA002188	CAB024961

GENE INFORMATION
Gene name	FABP4 (HGNC Symbol)
Synonyms	A-FABP, aP2
Description	Fatty acid binding protein 4, adipocyte (HGNC Symbol)
Entrez gene summary	FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
Chromosome	8
Cytoband	q21.13
Chromosome location (bp)	81478419 - 81483263
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170323 (version 83.38)
Entrez gene	2167
UniProt	P15090 (UniProt - Evidence at protein level)
neXtProt	NX_P15090
Antibodypedia	FABP4 antibodies

PROTEIN BROWSER

FABP4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FABP4-001 ENSP00000256104 ENST00000256104	P15090 [Direct mapping] Fatty acid-binding protein, adipocyte E7DVW4 [Target identity:100%; Query identity:100%] Epididymis secretory protein Li 104; Fatty acid binding protein 4, adipocyte Show all	Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001816 [cytokine production] GO:0005215 [transporter activity] GO:0005504 [fatty acid binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0006469 [negative regulation of protein kinase activity] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0019433 [triglyceride catabolic process] GO:0042632 [cholesterol homeostasis] GO:0044281 [small molecule metabolic process] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0050729 [positive regulation of inflammatory response] GO:0050872 [white fat cell differentiation] GO:0050873 [brown fat cell differentiation] GO:0070062 [extracellular exosome] GO:0071285 [cellular response to lithium ion] Show all	132 aa 14.7 kDa	No	0