Tissue expression of HOXB9 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	HOXB9
Gene description	Homeobox B9
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (epididymis)
GTEx:	Group enriched (small intestine, colon, kidney)
FANTOM5:	Group enriched (seminal vesicle, epididymis, kidney)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (epididymis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (small intestine, colon, kidney)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (seminal vesicle, epididymis, kidney)

GENE INFORMATION
Gene name	HOXB9 (HGNC Symbol)
Synonyms	HOX2, HOX2E
Description	Homeobox B9 (HGNC Symbol)
Entrez gene summary	This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.32
Chromosome location (bp)	48621159 - 48626356
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170689 (version 83.38)
Entrez gene	3219
UniProt	P17482 (UniProt - Evidence at protein level)
neXtProt	NX_P17482
Antibodypedia	HOXB9 antibodies

PROTEIN BROWSER

HOXB9-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HOXB9-001 ENSP00000309439 ENST00000311177	P17482 [Direct mapping] Homeobox protein Hox-B9 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005739 [mitochondrion] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0009952 [anterior/posterior pattern specification] GO:0030879 [mammary gland development] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048706 [embryonic skeletal system development] GO:0060070 [canonical Wnt signaling pathway] GO:0060326 [cell chemotaxis] Show all	250 aa 28.1 kDa	No	0