Expression of PRKCDBP in cancer - Summary

CANCER ATLAS

Gene description

Protein kinase C, delta binding protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055136

GENE INFORMATION
Gene name	PRKCDBP (HGNC Symbol)
Synonyms	cavin-3, CAVIN3, HSRBC, MGC20400, SRBC
Description	Protein kinase C, delta binding protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	6318946 - 6320647
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170955 (version 83.38)
Entrez gene	112464
UniProt	Q969G5 (UniProt - Evidence at protein level)
neXtProt	NX_Q969G5
Antibodypedia	PRKCDBP antibodies

PROTEIN BROWSER

PRKCDBP-001	PRKCDBP-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRKCDBP-001 ENSP00000307292 ENST00000303927	Q969G5 [Direct mapping] Protein kinase C delta-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005901 [caveola] GO:0030866 [cortical actin cytoskeleton organization] GO:0032922 [circadian regulation of gene expression] GO:0043234 [protein complex] GO:0051898 [negative regulation of protein kinase B signaling] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:1901003 [negative regulation of fermentation] Show all	261 aa 27.7 kDa	No	0
PRKCDBP-004 ENSP00000432047 ENST00000530979	E9PIE3 [Direct mapping] Protein kinase C delta-binding protein Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005080 [protein kinase C binding] GO:0005737 [cytoplasm] Show all	293 aa 31.1 kDa	No	0