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Hepatocellular carcinoma and endometrial cancers as well as several cases of pancreas and lung cancers showed moderate immunoreactivity. Remaining cancers were weakly stained or negative.
Most cancers showed weak to moderate cytoplasmic positivity.
GENE INFORMATION
Gene name
LRG1 (HGNC Symbol)
Synonyms
LRG
Description
Leucine-rich alpha-2-glycoprotein 1 (HGNC Symbol)
Entrez gene summary
The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]