Expression of TPPP in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Tubulin polymerization promoting protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036575	HPA036576

GENE INFORMATION
Gene name	TPPP (HGNC Symbol)
Synonyms	p25, p25alpha, TPPP/p25, TPPP1
Description	Tubulin polymerization promoting protein (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	659862 - 693395
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000171368 (version 83.38)
Entrez gene	11076
UniProt	O94811 (UniProt - Evidence at protein level)
neXtProt	NX_O94811
Antibodypedia	TPPP antibodies

PROTEIN BROWSER

TPPP-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TPPP-001 ENSP00000353785 ENST00000360578	O94811 [Direct mapping] Tubulin polymerization-promoting protein Q4L233 [Target identity:100%; Query identity:100%] Brain-specific protein p25 alpha, isoform CRA_b; Fibroblast growth factor-2 repression protein-1; Tubulin polymerization promoting protein; cDNA FLJ30358 fis, clone BRACE2007749, highly similar to Tubulin polymerization-promoting protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001578 [microtubule bundle formation] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0008017 [microtubule binding] GO:0015631 [tubulin binding] GO:0031334 [positive regulation of protein complex assembly] GO:0032273 [positive regulation of protein polymerization] GO:0043209 [myelin sheath] GO:0046785 [microtubule polymerization] GO:0048471 [perinuclear region of cytoplasm] Show all	219 aa 23.7 kDa	No	0