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Most of the malignant cells displayed weak to moderate nuclear and cytoplasmic positivity. Several malignant carcinoids along with a few squamous cell carcinomas, hepatocellular carcinomas, testis and renal cancers were strongly stained. Many prostate cancers were negative.
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007165 [signal transduction] GO:0022008 [neurogenesis] GO:0044212 [transcription regulatory region DNA binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding]
