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MTBP

CANCER ATLAS

Gene description

 MDM2 binding protein

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA025694

GENE INFORMATION

Gene name

 MTBP

Synonyms

Description

 MDM2 binding protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]

Chromosome

 8

Cytoband

 q24.12

Chromosome location (bp)

 120445400 - 120542133

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172167 (version 83.38)

Entrez gene

 27085

UniProt

 Q96DY7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96DY7

Antibodypedia

 MTBP antibodies

PROTEIN BROWSER
MTBP-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MTBP-001
ENSP00000303398
ENST00000305949
Q96DY7 [Direct mapping]
Mdm2-binding protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000776 [kinetochore]
GO:0000785 [chromatin]
GO:0005515 [protein binding]
GO:0007050 [cell cycle arrest]
GO:0007089 [traversing start control point of mitotic cell cycle]
GO:0008285 [negative regulation of cell proliferation]
GO:0034501 [protein localization to kinetochore]
GO:0045839 [negative regulation of mitotic nuclear division]
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 904 aa
102.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.