Tissue expression of C1QTNF4 - Summary - The Human Protein Atlas

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C1QTNF4

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	C1QTNF4
Gene description	C1q and tumor necrosis factor related protein 4
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (cerebral cortex)
GTEx:	Tissue enhanced (caudate)
FANTOM5:	Group enriched (caudate, cerebellum, brain, hippocampus)

Protein evidence

Evidence at protein level

Protein expression

Secreted expression in several tissues types

DATA RELIABILITY
Data reliability description	Antibody staining not consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Approved based on 1 antibody. HPA041032
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (caudate)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, cerebellum, brain, hippocampus)

GENE INFORMATION
Gene name	C1QTNF4 (HGNC Symbol)
Synonyms	CTRP4, ZACRP4
Description	C1q and tumor necrosis factor related protein 4 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p11.2
Chromosome location (bp)	47589664 - 47594659
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172247 (version 83.38)
Entrez gene	114900
UniProt	Q9BXJ3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXJ3
Antibodypedia	C1QTNF4 antibodies

PROTEIN BROWSER

C1QTNF4-001	C1QTNF4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C1QTNF4-001 ENSP00000302274 ENST00000302514	Q9BXJ3 [Direct mapping] Complement C1q tumor necrosis factor-related protein 4 Show all	SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005125 [cytokine activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] Show all	329 aa 35.3 kDa	Yes	0
C1QTNF4-002 ENSP00000434548 ENST00000530097	E9PPZ5 [Direct mapping] Complement C1q tumor necrosis factor-related protein 4 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	100 aa 10.6 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.