Expression of CFAP53 in cancer - Summary

CANCER ATLAS

Gene description

Cilia and flagella associated protein 53

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040595

GENE INFORMATION
Gene name	CFAP53 (HGNC Symbol)
Synonyms	CCDC11, FLJ32743
Description	Cilia and flagella associated protein 53 (HGNC Symbol)
Entrez gene summary	This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning. [provided by RefSeq, Aug 2015]
Chromosome	18
Cytoband	q21.1
Chromosome location (bp)	50227193 - 50266522
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172361 (version 83.38)
Entrez gene	220136
UniProt	Q96M91 (UniProt - Evidence at protein level)
neXtProt	NX_Q96M91
Antibodypedia	CFAP53 antibodies

PROTEIN BROWSER

CFAP53-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CFAP53-001 ENSP00000381553 ENST00000398545	Q96M91 [Direct mapping] Cilia- and flagella-associated protein 53 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005929 [cilium] GO:0008150 [biological_process] Show all	514 aa 61.8 kDa	No	0