Expression of ACOT12 in cancer - Summary

CANCER ATLAS

Gene description

Acyl-CoA thioesterase 12

Protein class

Enzymes, Predicted intracellular proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA037723	HPA037724

GENE INFORMATION
Gene name	ACOT12 (HGNC Symbol)
Synonyms	Cach, STARD15, THEAL
Description	Acyl-CoA thioesterase 12 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q14.1
Chromosome location (bp)	81330005 - 81394179
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172497 (version 83.38)
Entrez gene	134526
UniProt	Q8WYK0 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WYK0
Antibodypedia	ACOT12 antibodies

PROTEIN BROWSER

ACOT12-001	ACOT12-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACOT12-001 ENSP00000303246 ENST00000307624	Q8WYK0 [Direct mapping] Acyl-coenzyme A thioesterase 12 Show all	Enzymes ENZYME proteins Hydrolases Transporters Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005524 [ATP binding] GO:0005829 [cytosol] GO:0006084 [acetyl-CoA metabolic process] GO:0006090 [pyruvate metabolic process] GO:0006631 [fatty acid metabolic process] GO:0006637 [acyl-CoA metabolic process] GO:0008289 [lipid binding] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	555 aa 62 kDa	No	0
ACOT12-002 ENSP00000421628 ENST00000513751	Q8WYK0 [Direct mapping] Acyl-coenzyme A thioesterase 12 Show all	Enzymes ENZYME proteins Hydrolases Transporters Predicted intracellular proteins Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005829 [cytosol] GO:0006090 [pyruvate metabolic process] GO:0006631 [fatty acid metabolic process] GO:0006637 [acyl-CoA metabolic process] GO:0008289 [lipid binding] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	167 aa 18.3 kDa	No	0