Expression of NIPAL4 in cancer - Summary

CANCER ATLAS

Gene description

NIPA-like domain containing 4

Protein class

Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038259

GENE INFORMATION
Gene name	NIPAL4 (HGNC Symbol)
Synonyms	ICHYN
Description	NIPA-like domain containing 4 (HGNC Symbol)
Entrez gene summary	This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010]
Chromosome	5
Cytoband	q33.3
Chromosome location (bp)	157460019 - 157474717
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000172548 (version 83.38)
Entrez gene	348938
UniProt	Q0D2K0 (UniProt - Evidence at protein level)
neXtProt	NX_Q0D2K0
Antibodypedia	NIPAL4 antibodies

PROTEIN BROWSER

NIPAL4-001	NIPAL4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NIPAL4-001 ENSP00000311687 ENST00000311946	Q0D2K0 [Direct mapping] Magnesium transporter NIPA4 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0015095 [magnesium ion transmembrane transporter activity] GO:0015693 [magnesium ion transport] GO:0016021 [integral component of membrane] GO:1903830 [magnesium ion transmembrane transport] Show all	466 aa 50.1 kDa	No	9
NIPAL4-002 ENSP00000406456 ENST00000435489	Q0D2K0 [Direct mapping] Magnesium transporter NIPA4 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0015095 [magnesium ion transmembrane transporter activity] GO:0015693 [magnesium ion transport] GO:0016021 [integral component of membrane] GO:1903830 [magnesium ion transmembrane transport] Show all	447 aa 47.9 kDa	No	8