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RNA tissue category: Group enriched (lymph node, tonsil, appendix)
GENE INFORMATION
Gene name
CCL19 (HGNC Symbol)
Synonyms
CKb11, ELC, exodus-3, MIP-3b, SCYA19
Description
Chemokine (C-C motif) ligand 19 (HGNC Symbol)
Entrez gene summary
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]