Fields »
ABOUT
HELP
BLOG
CORO1B

GENERAL INFORMATION

Gene name

 CORO1B

Gene description

 Coronin, actin binding protein, 1B

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic and membranous expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA070456 , CAB017616
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CORO1B (HGNC Symbol)

Synonyms

 coronin-2

Description

 Coronin, actin binding protein, 1B (HGNC Symbol)

Entrez gene summary

 Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM, Mar 2008]

Chromosome

 11

Cytoband

 q13.2

Chromosome location (bp)

 67435510 - 67443821

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172725 (version 83.38)

Entrez gene

 57175

UniProt

 Q9BR76 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BR76

Antibodypedia

 CORO1B antibodies

PROTEIN BROWSER
CORO1B-001
CORO1B-008
CORO1B-201
CORO1B-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CORO1B-001
ENSP00000340211
ENST00000341356
Q9BR76 [Direct mapping]
Coronin-1B
A0A024R5K1 [Target identity:100%; Query identity:100%]
Coronin
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005884 [actin filament]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0015629 [actin cytoskeleton]
GO:0016477 [cell migration]
GO:0030027 [lamellipodium]
GO:0030036 [actin cytoskeleton organization]
GO:0031252 [cell leading edge]
GO:0031529 [ruffle organization]
GO:0034315 [regulation of Arp2/3 complex-mediated actin nucleation]
GO:0034316 [negative regulation of Arp2/3 complex-mediated actin nucleation]
GO:0035767 [endothelial cell chemotaxis]
GO:0036120 [cellular response to platelet-derived growth factor stimulus]
GO:0042060 [wound healing]
GO:0042802 [identical protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051015 [actin filament binding]
GO:0051017 [actin filament bundle assembly]
GO:0070062 [extracellular exosome]
GO:0071672 [negative regulation of smooth muscle cell chemotaxis]
GO:0071933 [Arp2/3 complex binding]
GO:0071944 [cell periphery]
GO:0090135 [actin filament branching]
GO:1902463 [protein localization to cell leading edge]
GO:2000394 [positive regulation of lamellipodium morphogenesis]
Show all
 489 aa
54.2 kDa 		No 0
CORO1B-008
ENSP00000438056
ENST00000545016
F5H0D2 [Direct mapping]
Coronin
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0015629 [actin cytoskeleton]
GO:0030036 [actin cytoskeleton organization]
GO:0051015 [actin filament binding]
Show all
 139 aa
15.3 kDa 		No 0
CORO1B-201
ENSP00000377471
ENST00000393893
Q9BR76 [Direct mapping]
Coronin-1B
A0A024R5K1 [Target identity:100%; Query identity:100%]
Coronin
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001725 [stress fiber]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005884 [actin filament]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0015629 [actin cytoskeleton]
GO:0016477 [cell migration]
GO:0030027 [lamellipodium]
GO:0030036 [actin cytoskeleton organization]
GO:0031252 [cell leading edge]
GO:0031529 [ruffle organization]
GO:0034315 [regulation of Arp2/3 complex-mediated actin nucleation]
GO:0034316 [negative regulation of Arp2/3 complex-mediated actin nucleation]
GO:0035767 [endothelial cell chemotaxis]
GO:0036120 [cellular response to platelet-derived growth factor stimulus]
GO:0042060 [wound healing]
GO:0042802 [identical protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0051015 [actin filament binding]
GO:0051017 [actin filament bundle assembly]
GO:0070062 [extracellular exosome]
GO:0071672 [negative regulation of smooth muscle cell chemotaxis]
GO:0071933 [Arp2/3 complex binding]
GO:0071944 [cell periphery]
GO:0090135 [actin filament branching]
GO:1902463 [protein localization to cell leading edge]
GO:2000394 [positive regulation of lamellipodium morphogenesis]
Show all
 489 aa
54.2 kDa 		No 0
CORO1B-202
ENSP00000486585
ENST00000627576
F5H390 [Direct mapping]
Coronin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0015629 [actin cytoskeleton]
Show all
 282 aa
31 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.