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Field

Term
Gene name

Class

Subclass

Chromosome

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In atlas

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Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RPL38
  • TISSUE

  • premium

    CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Ribosomal protein L38

Protein class

Predicted intracellular proteins, Ribosomal proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA052543

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Several breast, testis, liver, thyroid and urothelial cancers along with a few colorectal, endometrial, pancreatic and renal cancers displayed weak to moderate cytoplasmic and/or nuclear positivity. Remaining cancer cells were mainly negative.

GENE INFORMATION

Gene name

RPL38 (HGNC Symbol)

Synonyms

L38

Description

Ribosomal protein L38 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II receptor gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

74203582 - 74210655

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000172809 (version 83.38)

Entrez gene

6169

UniProt

P63173 (UniProt - Evidence at protein level)

neXtProt

NX_P63173

Antibodypedia

RPL38 antibodies

PROTEIN BROWSER

RPL38-001
RPL38-003
RPL38-005
RPL38-006
RPL38-007
RPL38-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPL38-001
ENSP00000309830
ENST00000311111
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0001501 [skeletal system development]
GO:0001503 [ossification]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0007605 [sensory perception of sound]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0033291 [eukaryotic 80S initiation complex]
GO:0034463 [90S preribosome assembly]
GO:0042474 [middle ear morphogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0048318 [axial mesoderm development]
Show all
70 aa
8.2 kDa
No 0
RPL38-003
ENSP00000390279
ENST00000439590
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
Show all
70 aa
8.2 kDa
No 0
RPL38-005
ENSP00000462580
ENST00000528433
J3KSP2 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
21 aa
2.6 kDa
No 0
RPL38-006
ENSP00000434243
ENST00000533498
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
Show all
70 aa
8.2 kDa
No 0
RPL38-007
ENSP00000462837
ENST00000534490
J3KT73 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
64 aa
7.6 kDa
No 0
RPL38-008
ENSP00000463312
ENST00000584577
J3QL01 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
67 aa
8 kDa
No 0

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