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RPL38

GENERAL INFORMATION

Gene name

 RPL38

Gene description

 Ribosomal protein L38

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA052543
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RPL38 (HGNC Symbol)

Synonyms

 L38

Description

 Ribosomal protein L38 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II receptor gene. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 q25.1

Chromosome location (bp)

 74203582 - 74210655

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172809 (version 83.38)

Entrez gene

 6169

UniProt

 P63173 (UniProt - Evidence at protein level)

neXtProt

 NX_P63173

Antibodypedia

 RPL38 antibodies

PROTEIN BROWSER
RPL38-001
RPL38-003
RPL38-005
RPL38-006
RPL38-007
RPL38-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL38-001
ENSP00000309830
ENST00000311111
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
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Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0001501 [skeletal system development]
GO:0001503 [ossification]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006417 [regulation of translation]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0007605 [sensory perception of sound]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0033291 [eukaryotic 80S initiation complex]
GO:0034463 [90S preribosome assembly]
GO:0042474 [middle ear morphogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0048318 [axial mesoderm development]
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 70 aa
8.2 kDa 		No 0
RPL38-003
ENSP00000390279
ENST00000439590
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
Show all
 70 aa
8.2 kDa 		No 0
RPL38-005
ENSP00000462580
ENST00000528433
J3KSP2 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 21 aa
2.6 kDa 		No 0
RPL38-006
ENSP00000434243
ENST00000533498
P63173 [Direct mapping]
60S ribosomal protein L38
A0A024R8P8 [Target identity:100%; Query identity:100%]
Ribosomal protein L38, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022618 [ribonucleoprotein complex assembly]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
Show all
 70 aa
8.2 kDa 		No 0
RPL38-007
ENSP00000462837
ENST00000534490
J3KT73 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 64 aa
7.6 kDa 		No 0
RPL38-008
ENSP00000463312
ENST00000584577
J3QL01 [Direct mapping]
60S ribosomal protein L38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
Show all
 67 aa
8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.