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SLC22A13

GENERAL INFORMATION

Gene name

 SLC22A13

Gene description

 Solute carrier family 22 (organic anion/urate transporter), member 13

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (kidney)
GTEx:Tissue enhanced (kidney)
FANTOM5:Tissue enriched (kidney)

Protein evidence

 Evidence at protein level

Protein expression

 Selective membranous expression in renal tubules.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA035603 , HPA035962
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (kidney)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (kidney)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (kidney)

GENE INFORMATION

Gene name

 SLC22A13 (HGNC Symbol)

Synonyms

 OAT10, OCTL1, OCTL3, ORCTL3

Description

 Solute carrier family 22 (organic anion/urate transporter), member 13 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine. [provided by RefSeq, Sep 2008]

Chromosome

 3

Cytoband

 p22.2

Chromosome location (bp)

 38265812 - 38278315

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000172940 (version 83.38)

Entrez gene

 9390

UniProt

 Q9Y226 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9Y226

Antibodypedia

 SLC22A13 antibodies

PROTEIN BROWSER
SLC22A13-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC22A13-001
ENSP00000310241
ENST00000311856
Q9Y226 [Direct mapping]
Solute carrier family 22 member 13
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Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
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GO:0005887 [integral component of plasma membrane]
GO:0015101 [organic cation transmembrane transporter activity]
GO:0015695 [organic cation transport]
GO:0015747 [urate transport]
GO:0016021 [integral component of membrane]
GO:0016324 [apical plasma membrane]
GO:0022857 [transmembrane transporter activity]
GO:0022891 [substrate-specific transmembrane transporter activity]
GO:0055085 [transmembrane transport]
GO:0070062 [extracellular exosome]
GO:0090416 [nicotinate transporter activity]
GO:2001142 [nicotinate transport]
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 551 aa
60.9 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.