Expression of HECTD4 in cancer - Summary

CANCER ATLAS

Gene description

HECT domain containing E3 ubiquitin protein ligase 4

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041062	HPA045473

GENE INFORMATION
Gene name	HECTD4 (HGNC Symbol)
Synonyms	C12orf51, FLJ34154, KIAA0614
Description	HECT domain containing E3 ubiquitin protein ligase 4 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.13
Chromosome location (bp)	112160188 - 112382439
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173064 (version 83.38)
Entrez gene	283450
UniProt
neXtProt
Antibodypedia	HECTD4 antibodies

PROTEIN BROWSER

HECTD4-001	HECTD4-009	HECTD4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HECTD4-001 ENSP00000366783 ENST00000377560	J3KPF0 [Direct mapping] Probable E3 ubiquitin-protein ligase HECTD4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] Show all	4416 aa 484.4 kDa	Yes	1
HECTD4-009 ENSP00000477079 ENST00000548588	V9GYT9 [Direct mapping] Probable E3 ubiquitin-protein ligase HECTD4 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		262 aa 29.4 kDa	No	0
HECTD4-201 ENSP00000449784 ENST00000550722	F8VWT9 [Direct mapping] Probable E3 ubiquitin-protein ligase HECTD4 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0016567 [protein ubiquitination] GO:0016874 [ligase activity] Show all	4284 aa 470 kDa	No	1