Expression of PPP1R3B in cancer - Summary

CANCER ATLAS

Gene description

Protein phosphatase 1, regulatory subunit 3B

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA028731

GENE INFORMATION
Gene name	PPP1R3B (HGNC Symbol)
Synonyms	FLJ14005, GL, PPP1R4
Description	Protein phosphatase 1, regulatory subunit 3B (HGNC Symbol)
Entrez gene summary	This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jan 2011]
Chromosome	8
Cytoband	p23.1
Chromosome location (bp)	9136255 - 9151574
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000173281 (version 83.38)
Entrez gene	79660
UniProt	Q86XI6 (UniProt - Evidence at protein level)
neXtProt	NX_Q86XI6
Antibodypedia	PPP1R3B antibodies

PROTEIN BROWSER

PPP1R3B-001	PPP1R3B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPP1R3B-001 ENSP00000308318 ENST00000310455	Q86XI6 [Direct mapping] Protein phosphatase 1 regulatory subunit 3B Show all	Predicted intracellular proteins Show all	GO:0000164 [protein phosphatase type 1 complex] GO:0004721 [phosphoprotein phosphatase activity] GO:0005515 [protein binding] GO:0005977 [glycogen metabolic process] GO:0005979 [regulation of glycogen biosynthetic process] GO:0005981 [regulation of glycogen catabolic process] GO:0006470 [protein dephosphorylation] GO:0019888 [protein phosphatase regulator activity] GO:0019899 [enzyme binding] GO:0042587 [glycogen granule] GO:0043231 [intracellular membrane-bounded organelle] GO:0050790 [regulation of catalytic activity] Show all	285 aa 32.7 kDa	No	0
PPP1R3B-002 ENSP00000428642 ENST00000519699	Q86XI6 [Direct mapping] Protein phosphatase 1 regulatory subunit 3B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005977 [glycogen metabolic process] GO:0005981 [regulation of glycogen catabolic process] Show all	285 aa 32.7 kDa	No	0