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PPP1R3B

GENERAL INFORMATION

Gene name

 PPP1R3B

Gene description

 Protein phosphatase 1, regulatory subunit 3B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA028731
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PPP1R3B (HGNC Symbol)

Synonyms

 FLJ14005, GL, PPP1R4

Description

 Protein phosphatase 1, regulatory subunit 3B (HGNC Symbol)

Entrez gene summary

 This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jan 2011]

Chromosome

 8

Cytoband

 p23.1

Chromosome location (bp)

 9136255 - 9151574

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000173281 (version 83.38)

Entrez gene

 79660

UniProt

 Q86XI6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86XI6

Antibodypedia

 PPP1R3B antibodies

PROTEIN BROWSER
PPP1R3B-001
PPP1R3B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PPP1R3B-001
ENSP00000308318
ENST00000310455
Q86XI6 [Direct mapping]
Protein phosphatase 1 regulatory subunit 3B
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Predicted intracellular proteins
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GO:0000164 [protein phosphatase type 1 complex]
GO:0004721 [phosphoprotein phosphatase activity]
GO:0005515 [protein binding]
GO:0005977 [glycogen metabolic process]
GO:0005979 [regulation of glycogen biosynthetic process]
GO:0005981 [regulation of glycogen catabolic process]
GO:0006470 [protein dephosphorylation]
GO:0019888 [protein phosphatase regulator activity]
GO:0019899 [enzyme binding]
GO:0042587 [glycogen granule]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0050790 [regulation of catalytic activity]
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 285 aa
32.7 kDa 		No 0
PPP1R3B-002
ENSP00000428642
ENST00000519699
Q86XI6 [Direct mapping]
Protein phosphatase 1 regulatory subunit 3B
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005977 [glycogen metabolic process]
GO:0005981 [regulation of glycogen catabolic process]
Show all
 285 aa
32.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.