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SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
Predicted intracellular proteins Plasma proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000790 [nuclear chromatin] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0000980 [RNA polymerase II distal enhancer sequence-specific DNA binding] GO:0001741 [XY body] GO:0003677 [DNA binding] GO:0003682 [chromatin binding] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006337 [nucleosome disassembly] GO:0006338 [chromatin remodeling] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007399 [nervous system development] GO:0008286 [insulin receptor signaling pathway] GO:0009887 [organ morphogenesis] GO:0016514 [SWI/SNF complex] GO:0030850 [prostate gland development] GO:0031492 [nucleosomal DNA binding] GO:0032435 [negative regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0043044 [ATP-dependent chromatin remodeling] GO:0043234 [protein complex] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0047485 [protein N-terminus binding] GO:0071564 [npBAF complex] GO:0071565 [nBAF complex] GO:0090544 [BAF-type complex]
