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Most cancer tissues displayed moderate cytoplasmic positivity. Colorectal, ovarian, thyroid, pancreatic and cholangiocarcinomas showed strong staining.
GENE INFORMATION
Gene name
CSPG4 (HGNC Symbol)
Synonyms
HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2
Description
Chondroitin sulfate proteoglycan 4 (HGNC Symbol)
Entrez gene summary
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008]