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REP15

CANCER ATLAS

Gene description

 RAB15 effector protein

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA040448
HPA059868

GENE INFORMATION

Gene name

 REP15 (HGNC Symbol)

Synonyms

 RAB15EP

Description

 RAB15 effector protein (HGNC Symbol)

Entrez gene summary

 REP15 is a binding partner of the RAB GTPase family member RAB15 that facilitates transferrin receptor (TFRC; MIM 190010) recycling from the endocytic recycling compartment (Strick and Elferink, 2005 [PubMed 16195351]).[supplied by OMIM, Mar 2008]

Chromosome

 12

Cytoband

 p11.22

Chromosome location (bp)

 27696519 - 27697596

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174236 (version 83.38)

Entrez gene

 387849

UniProt

 Q6BDI9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6BDI9

Antibodypedia

 REP15 antibodies

PROTEIN BROWSER
REP15-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
REP15-001
ENSP00000310335
ENST00000310791
Q6BDI9 [Direct mapping]
Rab15 effector protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001881 [receptor recycling]
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005515 [protein binding]
GO:0010008 [endosome membrane]
GO:0031901 [early endosome membrane]
GO:0033572 [transferrin transport]
GO:0048471 [perinuclear region of cytoplasm]
GO:0055037 [recycling endosome]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
Show all
 236 aa
26.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.