Expression of PITPNA in cancer - Summary

CANCER ATLAS

Gene description

Phosphatidylinositol transfer protein, alpha

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Head and neck cancer

STAINING SUMMARY

HPA000528

GENE INFORMATION
Gene name	PITPNA (HGNC Symbol)
Synonyms	PITPN, VIB1A
Description	Phosphatidylinositol transfer protein, alpha (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
Chromosome	17
Cytoband	p13.3
Chromosome location (bp)	1517718 - 1562816
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174238 (version 83.38)
Entrez gene	5306
UniProt	Q00169 (UniProt - Evidence at protein level)
neXtProt	NX_Q00169
Antibodypedia	PITPNA antibodies

PROTEIN BROWSER

PITPNA-001	PITPNA-003	PITPNA-004	PITPNA-005	PITPNA-006	PITPNA-007	PITPNA-008	PITPNA-009	PITPNA-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PITPNA-001 ENSP00000316809 ENST00000313486	Q00169 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform V9HWC5 [Target identity:100%; Query identity:100%] Epididymis secretory protein Li 36 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0006629 [lipid metabolic process] GO:0006810 [transport] GO:0007411 [axon guidance] GO:0007601 [visual perception] GO:0008289 [lipid binding] GO:0008525 [phosphatidylcholine transporter activity] GO:0008526 [phosphatidylinositol transporter activity] GO:0015914 [phospholipid transport] GO:0043209 [myelin sheath] GO:0070062 [extracellular exosome] Show all	270 aa 31.8 kDa	No	0
PITPNA-003 ENSP00000461245 ENST00000574991	I3L4H1 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	209 aa 24.6 kDa	No	0
PITPNA-004 ENSP00000461539 ENST00000573056	I3L4U7 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	121 aa 13.5 kDa	No	0
PITPNA-005 ENSP00000461140 ENST00000575895	I3L4C0 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	115 aa 13.3 kDa	No	0
PITPNA-006 ENSP00000460771 ENST00000573231	I3L3W1 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	44 aa 5.3 kDa	No	0
PITPNA-007 ENSP00000461801 ENST00000576761	I3NI10 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	66 aa 7.8 kDa	No	0
PITPNA-008 ENSP00000460983 ENST00000576722	I3L459 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	142 aa 16.7 kDa	No	0
PITPNA-009 ENSP00000460008 ENST00000576010	I3L2X8 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	83 aa 9.7 kDa	No	0
PITPNA-201 ENSP00000441869 ENST00000539476	F5GWE5 [Direct mapping] Phosphatidylinositol transfer protein alpha isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	270 aa 31.8 kDa	No	0