Expression of RAB1B in cancer - Summary

CANCER ATLAS

Gene description

RAB1B, member RAS oncogene family

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA056141	CAB010225

GENE INFORMATION
Gene name	RAB1B
Synonyms
Description	RAB1B, member RAS oncogene family (HGNC Symbol)
Entrez gene summary	Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	66268533 - 66277492
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174903 (version 83.38)
Entrez gene	81876
UniProt	Q9H0U4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H0U4
Antibodypedia	RAB1B antibodies

PROTEIN BROWSER

RAB1B-001	RAB1B-003	RAB1B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB1B-001 ENSP00000310226 ENST00000311481	Q9H0U4 [Direct mapping] Ras-related protein Rab-1B Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005794 [Golgi apparatus] GO:0006886 [intracellular protein transport] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0006913 [nucleocytoplasmic transport] GO:0006914 [autophagy] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0019068 [virion assembly] GO:0032482 [Rab protein signal transduction] GO:0034045 [pre-autophagosomal structure membrane] GO:0070062 [extracellular exosome] GO:1903020 [positive regulation of glycoprotein metabolic process] GO:2000785 [regulation of autophagosome assembly] Show all	201 aa 22.2 kDa	No	0
RAB1B-003 ENSP00000435195 ENST00000527397	E9PLD0 [Direct mapping] Ras-related protein Rab-1B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006886 [intracellular protein transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0032482 [Rab protein signal transduction] Show all	169 aa 18.5 kDa	No	0
RAB1B-201 ENSP00000477893 ENST00000615245	A0A087WTI1 [Direct mapping] Ras-related protein Rab-1B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006886 [intracellular protein transport] GO:0007165 [signal transduction] GO:0007264 [small GTPase mediated signal transduction] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0032482 [Rab protein signal transduction] Show all	162 aa 18.7 kDa	No	0