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RAB1B

GENERAL INFORMATION

Gene name

 RAB1B

Gene description

 RAB1B, member RAS oncogene family

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 2 antibodies.
HPA056141 , CAB010225
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Duodenum

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RAB1B

Synonyms

Description

 RAB1B, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

 Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]

Chromosome

 11

Cytoband

 q13.2

Chromosome location (bp)

 66268533 - 66277492

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000174903 (version 83.38)

Entrez gene

 81876

UniProt

 Q9H0U4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H0U4

Antibodypedia

 RAB1B antibodies

PROTEIN BROWSER
RAB1B-001
RAB1B-003
RAB1B-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB1B-001
ENSP00000310226
ENST00000311481
Q9H0U4 [Direct mapping]
Ras-related protein Rab-1B
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005739 [mitochondrion]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment]
GO:0005794 [Golgi apparatus]
GO:0006886 [intracellular protein transport]
GO:0006888 [ER to Golgi vesicle-mediated transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0006914 [autophagy]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019068 [virion assembly]
GO:0032482 [Rab protein signal transduction]
GO:0034045 [pre-autophagosomal structure membrane]
GO:0070062 [extracellular exosome]
GO:1903020 [positive regulation of glycoprotein metabolic process]
GO:2000785 [regulation of autophagosome assembly]
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 201 aa
22.2 kDa 		No 0
RAB1B-003
ENSP00000435195
ENST00000527397
E9PLD0 [Direct mapping]
Ras-related protein Rab-1B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006886 [intracellular protein transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
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 169 aa
18.5 kDa 		No 0
RAB1B-201
ENSP00000477893
ENST00000615245
A0A087WTI1 [Direct mapping]
Ras-related protein Rab-1B
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005789 [endoplasmic reticulum membrane]
GO:0006886 [intracellular protein transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0032482 [Rab protein signal transduction]
Show all
 162 aa
18.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.