Expression of GPR149 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 149

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018020

GENE INFORMATION
Gene name	GPR149 (HGNC Symbol)
Synonyms	IEDA, PGR10
Description	G protein-coupled receptor 149 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q25.2
Chromosome location (bp)	154337672 - 154429715
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174948 (version 83.38)
Entrez gene	344758
UniProt	Q86SP6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86SP6
Antibodypedia	GPR149 antibodies

PROTEIN BROWSER

GPR149-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR149-001 ENSP00000374390 ENST00000389740	Q86SP6 [Direct mapping] Probable G-protein coupled receptor 149 Q2MKA6 [Target identity:100%; Query identity:100%] G protein-coupled receptor 149; HCG2022073 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0001546 [preantral ovarian follicle growth] GO:0001547 [antral ovarian follicle growth] GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007218 [neuropeptide signaling pathway] GO:0007268 [synaptic transmission] GO:0016021 [integral component of membrane] GO:0042923 [neuropeptide binding] GO:0043005 [neuron projection] GO:0060280 [negative regulation of ovulation] Show all	731 aa 81 kDa	No	6