Tissue expression of GPR149 - Summary - The Human Protein Atlas

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GPR149

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GPR149
Gene description	G protein-coupled receptor 149
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (seminal vesicle)
GTEx:	Group enriched (caudate, pituitary gland, hypothalamus)
FANTOM5:	Group enriched (caudate, pituitary gland)

Protein evidence

Evidence at transcript level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA018020
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (seminal vesicle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, pituitary gland, hypothalamus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, pituitary gland)

GENE INFORMATION
Gene name	GPR149 (HGNC Symbol)
Synonyms	IEDA, PGR10
Description	G protein-coupled receptor 149 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q25.2
Chromosome location (bp)	154337672 - 154429715
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000174948 (version 83.38)
Entrez gene	344758
UniProt	Q86SP6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86SP6
Antibodypedia	GPR149 antibodies

PROTEIN BROWSER

GPR149-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR149-001 ENSP00000374390 ENST00000389740	Q86SP6 [Direct mapping] Probable G-protein coupled receptor 149 Q2MKA6 [Target identity:100%; Query identity:100%] G protein-coupled receptor 149; HCG2022073 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0001546 [preantral ovarian follicle growth] GO:0001547 [antral ovarian follicle growth] GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007218 [neuropeptide signaling pathway] GO:0007268 [synaptic transmission] GO:0016021 [integral component of membrane] GO:0042923 [neuropeptide binding] GO:0043005 [neuron projection] GO:0060280 [negative regulation of ovulation] Show all	731 aa 81 kDa	No	6

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.