Cell atlas - ASCL3 - The Human Protein Atlas

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ASCL3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ASCL3
Gene description	Achaete-scute family bHLH transcription factor 3
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ASCL3 (HGNC Symbol)
Synonyms	bHLHa42, HASH3, Sgn1
Description	Achaete-scute family bHLH transcription factor 3 (HGNC Symbol)
Entrez gene summary	Basic helix-loop-helix transcription factors, such as ASCL3, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	8937579 - 8938211
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000176009 (version 83.38)
Entrez gene	56676
UniProt	Q9NQ33 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NQ33
Antibodypedia	ASCL3 antibodies

PROTEIN BROWSER

ASCL3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASCL3-001 ENSP00000435770 ENST00000531618	Q9NQ33 [Direct mapping] Achaete-scute homolog 3 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005667 [transcription factor complex] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046983 [protein dimerization activity] Show all	181 aa 20.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.