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FOXL1

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GENERAL INFORMATION

Gene name

 FOXL1

Gene description

 Forkhead box L1

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (U-87 MG, PC-3, CAPAN-2)

Protein evidence

 Evidence at transcript level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-87 MG, PC-3, CAPAN-2)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 FOXL1 (HGNC Symbol)

Synonyms

 FKH6, FKHL11, FREAC7

Description

 Forkhead box L1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]

Chromosome

 16

Cytoband

 q24.1

Chromosome location (bp)

 86576368 - 86582160

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000176678 (version 83.38)

Entrez gene

 2300

UniProt

 Q12952 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q12952

Antibodypedia

 FOXL1 antibodies

PROTEIN BROWSER
FOXL1-001
FOXL1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FOXL1-001
ENSP00000326272
ENST00000320241
Q12952 [Direct mapping]
Forkhead box protein L1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007495 [visceral mesoderm-endoderm interaction involved in midgut development]
GO:0007507 [heart development]
GO:0008301 [DNA binding, bending]
GO:0009653 [anatomical structure morphogenesis]
GO:0009887 [organ morphogenesis]
GO:0030111 [regulation of Wnt signaling pathway]
GO:0030154 [cell differentiation]
GO:0030166 [proteoglycan biosynthetic process]
GO:0043565 [sequence-specific DNA binding]
GO:0061146 [Peyer's patch morphogenesis]
Show all
 345 aa
36.5 kDa 		No 0
FOXL1-002
ENSP00000472376
ENST00000593625
M0R279 [Direct mapping]
Forkhead box protein L1
Show all
Predicted intracellular proteins
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0009653 [anatomical structure morphogenesis]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
Show all
 114 aa
12.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.