Tissue expression of FOXL1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FOXL1
Gene description	Forkhead box L1
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (gallbladder)
GTEx:	Mixed
FANTOM5:	Tissue enhanced (gallbladder)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (gallbladder)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (gallbladder)

GENE INFORMATION
Gene name	FOXL1 (HGNC Symbol)
Synonyms	FKH6, FKHL11, FREAC7
Description	Forkhead box L1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]
Chromosome	16
Cytoband	q24.1
Chromosome location (bp)	86576368 - 86582160
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000176678 (version 83.38)
Entrez gene	2300
UniProt	Q12952 (UniProt - Evidence at transcript level)
neXtProt	NX_Q12952
Antibodypedia	FOXL1 antibodies

PROTEIN BROWSER

FOXL1-001	FOXL1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FOXL1-001 ENSP00000326272 ENST00000320241	Q12952 [Direct mapping] Forkhead box protein L1 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007275 [multicellular organismal development] GO:0007495 [visceral mesoderm-endoderm interaction involved in midgut development] GO:0007507 [heart development] GO:0008301 [DNA binding, bending] GO:0009653 [anatomical structure morphogenesis] GO:0009887 [organ morphogenesis] GO:0030111 [regulation of Wnt signaling pathway] GO:0030154 [cell differentiation] GO:0030166 [proteoglycan biosynthetic process] GO:0043565 [sequence-specific DNA binding] GO:0061146 [Peyer's patch morphogenesis] Show all	345 aa 36.5 kDa	No	0
FOXL1-002 ENSP00000472376 ENST00000593625	M0R279 [Direct mapping] Forkhead box protein L1 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0009653 [anatomical structure morphogenesis] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] Show all	114 aa 12.8 kDa	No	0