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Cancer tissues displayed moderate cytoplasmic positivity. Additional membranous staining was observed in pancreatic cancers. A few cases of renal, lung and urothelial cancers were strongly stained. Gliomas and lymphomas, several cases of melanomas and testicular cancers were negative.
GENE INFORMATION
Gene name
EPS8L2 (HGNC Symbol)
Synonyms
FLJ21935, FLJ22171, MGC3088
Description
EPS8-like 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]