Cell atlas - CHD9 - The Human Protein Atlas

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CHD9

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Plasma membrane

Human cell
	Cytosol
	Plasma Membrane

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GENERAL INFORMATION
Gene name	CHD9
Gene description	Chromodomain helicase DNA binding protein 9
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA042053
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol.

Main location

Plasma membrane (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA042053	A-431	Plasma membrane
	HPA042053	A-431	Cytosol
	HPA042053	U-2 OS	Plasma membrane
	HPA042053	U-2 OS	Cytosol
	HPA042053	U-251 MG	Nuclear speckles
			Plasma membrane
			Cytosol

GENE INFORMATION
Gene name	CHD9 (HGNC Symbol)
Synonyms	BC022889, FLJ12178, KIAA0308
Description	Chromodomain helicase DNA binding protein 9 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q12.2
Chromosome location (bp)	53055033 - 53329150
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177200 (version 83.38)
Entrez gene	80205
UniProt	Q3L8U1 (UniProt - Evidence at protein level)
neXtProt	NX_Q3L8U1
Antibodypedia	CHD9 antibodies

PROTEIN BROWSER

CHD9-001	CHD9-002	CHD9-003	CHD9-004	CHD9-010	CHD9-011	CHD9-012	CHD9-020	CHD9-201	CHD9-202	CHD9-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CHD9-001 ENSP00000457466 ENST00000566029	Q3L8U1 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] GO:0016817 [hydrolase activity, acting on acid anhydrides] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	2881 aa 324.1 kDa	No	0
CHD9-002 ENSP00000456793 ENST00000565832	H3BSP3 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] Show all	632 aa 70.8 kDa	No	0
CHD9-003 ENSP00000455307 ENST00000564845	Q3L8U1 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] GO:0016817 [hydrolase activity, acting on acid anhydrides] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	2881 aa 324.1 kDa	No	0
CHD9-004 ENSP00000457355 ENST00000565803	H3BTW3 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] GO:0005634 [nucleus] Show all	1099 aa 127.3 kDa	No	0
CHD9-010 ENSP00000457929 ENST00000563410	H3BV31 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		53 aa 5.8 kDa	No	0
CHD9-011 ENSP00000460155 ENST00000562785	I3L340 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		91 aa 10.5 kDa	No	0
CHD9-012 ENSP00000456415 ENST00000565442	H3BRU9 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		125 aa 14.3 kDa	No	0
CHD9-020 ENSP00000381522 ENST00000398510	Q3L8U1 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] GO:0016817 [hydrolase activity, acting on acid anhydrides] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	2897 aa 326 kDa	No	0
CHD9-201 ENSP00000396345 ENST00000447540	Q3L8U1 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0016568 [chromatin modification] GO:0016817 [hydrolase activity, acting on acid anhydrides] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] Show all	2897 aa 326 kDa	No	0
CHD9-202 ENSP00000478361 ENST00000615216	A0A087WU44 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008152 [metabolic process] GO:0016817 [hydrolase activity, acting on acid anhydrides] Show all	963 aa 105.9 kDa	No	0
CHD9-203 ENSP00000482842 ENST00000622617	A0A087WU44 [Direct mapping] Chromodomain-helicase-DNA-binding protein 9 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008152 [metabolic process] GO:0016817 [hydrolase activity, acting on acid anhydrides] Show all	963 aa 105.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.