Expression of GJD4 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Gap junction protein, delta 4, 40.1kDa

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038266

GENE INFORMATION
Gene name	GJD4 (HGNC Symbol)
Synonyms	CX40.1, FLJ90023
Description	Gap junction protein, delta 4, 40.1kDa (HGNC Symbol)
Entrez gene summary	Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
Chromosome	10
Cytoband	p11.21
Chromosome location (bp)	35605410 - 35608935
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000177291 (version 83.38)
Entrez gene	219770
UniProt	Q96KN9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96KN9
Antibodypedia	GJD4 antibodies

PROTEIN BROWSER

GJD4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GJD4-001 ENSP00000315070 ENST00000321660	Q96KN9 [Direct mapping] Gap junction delta-4 protein Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0005922 [connexon complex] GO:0007154 [cell communication] GO:0014717 [regulation of satellite cell activation involved in skeletal muscle regeneration] GO:0016021 [integral component of membrane] Show all	370 aa 40.1 kDa	No	4