Expression of WDR6 in cancer - Summary - The Human Protein Atlas

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WDR6

TISSUE

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CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

WD repeat domain 6

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042622

GENE INFORMATION
Gene name	WDR6
Synonyms
Description	WD repeat domain 6 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. [provided by RefSeq, Aug 2008]
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	49007062 - 49015953
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178252 (version 83.38)
Entrez gene	11180
UniProt	Q9NNW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NNW5
Antibodypedia	WDR6 antibodies

PROTEIN BROWSER

WDR6-001	WDR6-005	WDR6-008	WDR6-009	WDR6-010	WDR6-020	WDR6-022	WDR6-023	WDR6-024	WDR6-201	WDR6-202	WDR6-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WDR6-001 ENSP00000378857 ENST00000395474	A0A087X295 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0043234 [protein complex] GO:0043560 [insulin receptor substrate binding] Show all	1151 aa 125 kDa	No	0
WDR6-005 ENSP00000412195 ENST00000415265	E9PBK6 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	569 aa 62.2 kDa	No	0
WDR6-008 ENSP00000413432 ENST00000448293	E9PDU5 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] Show all	1070 aa 116.2 kDa	No	0
WDR6-009 ENSP00000390740 ENST00000419837	C9JFP6 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		99 aa 11.5 kDa	No	0
WDR6-010 ENSP00000477418 ENST00000429900	V9GZ48 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		31 aa 3.5 kDa	No	0
WDR6-020 ENSP00000387692 ENST00000438660	C9K020 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] Show all	271 aa 30.3 kDa	No	0
WDR6-022 ENSP00000477087 ENST00000489427	V9GYU1 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		125 aa 14.2 kDa	No	0
WDR6-023 ENSP00000477463 ENST00000491365	V9GZ65 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		35 aa 4 kDa	No	0
WDR6-024 ENSP00000477389 ENST00000608424	Q9NNW5 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0007050 [cell cycle arrest] GO:0008180 [COP9 signalosome] GO:0008285 [negative regulation of cell proliferation] GO:0010507 [negative regulation of autophagy] GO:0044822 [poly(A) RNA binding] Show all	1121 aa 121.7 kDa	No	0
WDR6-201 ENSP00000484799 ENST00000610967	A0A087X295 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	1151 aa 125 kDa	No	0
WDR6-202 ENSP00000482289 ENST00000615452	Q6PKC6 [Direct mapping] WD repeat-containing protein 6; WDR6 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	289 aa 32.1 kDa	No	0
WDR6-203 ENSP00000487056 ENST00000627177	F8WE36 [Direct mapping] WD repeat-containing protein 6 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		68 aa 7.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.