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SNX18

CANCER ATLAS

Gene description

 Sorting nexin 18

Protein class

 Plasma proteins, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037800

GENE INFORMATION

Gene name

 SNX18 (HGNC Symbol)

Synonyms

 SH3PX2, SH3PXD3B, SNAG1

Description

 Sorting nexin 18 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q11.2

Chromosome location (bp)

 54517759 - 54546585

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000178996 (version 83.38)

Entrez gene

 112574

UniProt

 Q96RF0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96RF0

Antibodypedia

 SNX18 antibodies

PROTEIN BROWSER
SNX18-001
SNX18-002
SNX18-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SNX18-001
ENSP00000317332
ENST00000326277
Q96RF0 [Direct mapping]
Sorting nexin-18
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005515 [protein binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005768 [endosome]
GO:0006886 [intracellular protein transport]
GO:0006897 [endocytosis]
GO:0007067 [mitotic nuclear division]
GO:0010008 [endosome membrane]
GO:0015031 [protein transport]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0016050 [vesicle organization]
GO:0016197 [endosomal transport]
GO:0030136 [clathrin-coated vesicle]
GO:0030426 [growth cone]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0031234 [extrinsic component of cytoplasmic side of plasma membrane]
GO:0035091 [phosphatidylinositol binding]
GO:0036089 [cleavage furrow formation]
GO:0043025 [neuronal cell body]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 628 aa
68.9 kDa 		No 0
SNX18-002
ENSP00000370817
ENST00000381410
Q96RF0 [Direct mapping]
Sorting nexin-18
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005515 [protein binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005768 [endosome]
GO:0006886 [intracellular protein transport]
GO:0006897 [endocytosis]
GO:0007067 [mitotic nuclear division]
GO:0010008 [endosome membrane]
GO:0015031 [protein transport]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0016050 [vesicle organization]
GO:0016197 [endosomal transport]
GO:0030136 [clathrin-coated vesicle]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0031234 [extrinsic component of cytoplasmic side of plasma membrane]
GO:0035091 [phosphatidylinositol binding]
GO:0036089 [cleavage furrow formation]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 624 aa
69 kDa 		No 0
SNX18-201
ENSP00000342276
ENST00000343017
Q96RF0 [Direct mapping]
Sorting nexin-18
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000281 [mitotic cytokinesis]
GO:0005515 [protein binding]
GO:0005546 [phosphatidylinositol-4,5-bisphosphate binding]
GO:0005768 [endosome]
GO:0006886 [intracellular protein transport]
GO:0006897 [endocytosis]
GO:0007067 [mitotic nuclear division]
GO:0010008 [endosome membrane]
GO:0015031 [protein transport]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0016050 [vesicle organization]
GO:0016197 [endosomal transport]
GO:0030136 [clathrin-coated vesicle]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0031234 [extrinsic component of cytoplasmic side of plasma membrane]
GO:0035091 [phosphatidylinositol binding]
GO:0036089 [cleavage furrow formation]
GO:0043547 [positive regulation of GTPase activity]
GO:0070062 [extracellular exosome]
Show all
 591 aa
64.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.