Tissue expression of EDC3 - Summary - The Human Protein Atlas

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EDC3

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	EDC3
Gene description	Enhancer of mRNA decapping 3
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	14
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Mainly cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA040650 , HPA044206
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	EDC3 (HGNC Symbol)
Synonyms	FLJ21128, hYjeF_N2-15q23, LSM16, YJDC, YJEFN2
Description	Enhancer of mRNA decapping 3 (HGNC Symbol)
Entrez gene summary	EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]
Chromosome	15
Cytoband	q24.1
Chromosome location (bp)	74630558 - 74696292
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179151 (version 83.38)
Entrez gene	80153
UniProt	Q96F86 (UniProt - Evidence at protein level)
neXtProt	NX_Q96F86
Antibodypedia	EDC3 antibodies

PROTEIN BROWSER

EDC3-001	EDC3-003	EDC3-004	EDC3-005	EDC3-007	EDC3-009	EDC3-010	EDC3-012	EDC3-013	EDC3-014	EDC3-015	EDC3-016	EDC3-017	EDC3-018

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EDC3-001 ENSP00000320503 ENST00000315127	Q96F86 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000932 [cytoplasmic mRNA processing body] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0042802 [identical protein binding] GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] GO:1990174 [phosphodiesterase decapping endonuclease activity] Show all	508 aa 56.1 kDa	No	0
EDC3-003 ENSP00000401343 ENST00000426797	Q96F86 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000932 [cytoplasmic mRNA processing body] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0042802 [identical protein binding] GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] GO:1990174 [phosphodiesterase decapping endonuclease activity] Show all	508 aa 56.1 kDa	No	0
EDC3-004 ENSP00000455580 ENST00000568176	Q96F86 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000932 [cytoplasmic mRNA processing body] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0042802 [identical protein binding] GO:0043928 [exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] GO:1990174 [phosphodiesterase decapping endonuclease activity] Show all	508 aa 56.1 kDa	No	0
EDC3-005 ENSP00000455393 ENST00000562174	H3BPN4 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		213 aa 23.3 kDa	No	0
EDC3-007 ENSP00000457128 ENST00000562974	H3BTD6 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		68 aa 7.8 kDa	No	0
EDC3-009 ENSP00000456805 ENST00000566219	H3BSQ0 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		163 aa 18.5 kDa	No	0
EDC3-010 ENSP00000455589 ENST00000569561	H3BQ37 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		178 aa 19.2 kDa	No	0
EDC3-012 ENSP00000455682 ENST00000566119	H3BQA1 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		31 aa 3.2 kDa	No	0
EDC3-013 ENSP00000457170 ENST00000570138	H3BTH0 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		101 aa 10.6 kDa	No	0
EDC3-014 ENSP00000454317 ENST00000563292	H3BMB8 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		92 aa 9.8 kDa	No	0
EDC3-015 ENSP00000457156 ENST00000567813	H3BTF8 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		54 aa 5.8 kDa	No	0
EDC3-016 ENSP00000455503 ENST00000563009	H3BPW9 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		253 aa 28 kDa	No	0
EDC3-017 ENSP00000457523 ENST00000566243	H3BU87 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		131 aa 13.8 kDa	No	0
EDC3-018 ENSP00000455870 ENST00000566828	H3BQP5 [Direct mapping] Enhancer of mRNA-decapping protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		123 aa 13 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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