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ZFPM1

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GENERAL INFORMATION

Gene name

 ZFPM1

Gene description

 Zinc finger protein, FOG family member 1

Protein class

 Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

RNA cell category

 Cell line enhanced (K-562)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (approved)

Additional location

 In addition localized to the Cytosol (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA046603
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (K-562)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

 Nucleoplasm (approved)

Additional location

 Cytosol (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA046603 CACO-2 Nucleoplasm
HPA046603 SH-SY5Y Nucleoplasm
Vesicles
Cytosol
HPA046603 U-2 OS Nucleoplasm
Cytosol

GENE INFORMATION

Gene name

 ZFPM1 (HGNC Symbol)

Synonyms

 FOG, FOG1, ZC2HC11A, ZNF89A

Description

 Zinc finger protein, FOG family member 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 16

Cytoband

 q24.2

Chromosome location (bp)

 88453317 - 88537016

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179588 (version 83.38)

Entrez gene

 161882

UniProt

 Q8IX07 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IX07

Antibodypedia

 ZFPM1 antibodies

PROTEIN BROWSER
ZFPM1-001
ZFPM1-002
ZFPM1-003
ZFPM1-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZFPM1-001
ENSP00000326630
ENST00000319555
Q8IX07 [Direct mapping]
Zinc finger protein ZFPM1
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Predicted intracellular proteins
Plasma proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding]
GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0002295 [T-helper cell lineage commitment]
GO:0003151 [outflow tract morphogenesis]
GO:0003181 [atrioventricular valve morphogenesis]
GO:0003192 [mitral valve formation]
GO:0003195 [tricuspid valve formation]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription factor complex]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007507 [heart development]
GO:0007596 [blood coagulation]
GO:0008134 [transcription factor binding]
GO:0010724 [regulation of definitive erythrocyte differentiation]
GO:0017053 [transcriptional repressor complex]
GO:0030218 [erythrocyte differentiation]
GO:0030219 [megakaryocyte differentiation]
GO:0030220 [platelet formation]
GO:0030851 [granulocyte differentiation]
GO:0032091 [negative regulation of protein binding]
GO:0032642 [regulation of chemokine production]
GO:0035162 [embryonic hemopoiesis]
GO:0035855 [megakaryocyte development]
GO:0045078 [positive regulation of interferon-gamma biosynthetic process]
GO:0045403 [negative regulation of interleukin-4 biosynthetic process]
GO:0045599 [negative regulation of fat cell differentiation]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0048872 [homeostasis of number of cells]
GO:0055008 [cardiac muscle tissue morphogenesis]
GO:0060318 [definitive erythrocyte differentiation]
GO:0060319 [primitive erythrocyte differentiation]
GO:0060377 [negative regulation of mast cell differentiation]
GO:0060412 [ventricular septum morphogenesis]
GO:0060413 [atrial septum morphogenesis]
GO:0071733 [transcriptional activation by promoter-enhancer looping]
Show all
 1006 aa
104.9 kDa 		No 0
ZFPM1-002
ENSP00000484216
ENST00000563351
A0A087X1H8 [Direct mapping]
Zinc finger protein ZFPM1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0007507 [heart development]
GO:0030218 [erythrocyte differentiation]
GO:0030219 [megakaryocyte differentiation]
Show all
 117 aa
13.2 kDa 		No 0
ZFPM1-003
ENSP00000480412
ENST00000562437
A0A087WWQ0 [Direct mapping]
Zinc finger protein ZFPM1; Zinc finger protein, multitype 1, isoform CRA_b
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0007507 [heart development]
GO:0030218 [erythrocyte differentiation]
GO:0030219 [megakaryocyte differentiation]
Show all
 151 aa
16.3 kDa 		No 0
ZFPM1-006
ENSP00000482796
ENST00000569086
A0A087WZP1 [Direct mapping]
Zinc finger protein ZFPM1; Zinc finger protein, multitype 1, isoform CRA_c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0007507 [heart development]
GO:0030218 [erythrocyte differentiation]
GO:0030219 [megakaryocyte differentiation]
Show all
 158 aa
17.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.