Cell atlas - CRIPAK - The Human Protein Atlas

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CRIPAK

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CRIPAK
Gene description	Cysteine-rich PAK1 inhibitor
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CRIPAK (HGNC Symbol)
Synonyms	FLJ34443
Description	Cysteine-rich PAK1 inhibitor (HGNC Symbol)
Entrez gene summary	CRIPAK is a negative regulator of PAK1 (MIM 602590) that is upregulated by estrogen (Talukder et al., 2006 [PubMed 16278681]).[supplied by OMIM, Mar 2008]
Chromosome	4
Cytoband	p16.3
Chromosome location (bp)	1391552 - 1395989
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179979 (version 83.38)
Entrez gene	285464
UniProt	Q8N1N5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N1N5
Antibodypedia	CRIPAK antibodies

PROTEIN BROWSER

CRIPAK-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRIPAK-001 ENSP00000323978 ENST00000324803	Q8N1N5 [Direct mapping] Cysteine-rich PAK1 inhibitor Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0006469 [negative regulation of protein kinase activity] GO:0033147 [negative regulation of intracellular estrogen receptor signaling pathway] GO:0043627 [response to estrogen] GO:0051493 [regulation of cytoskeleton organization] Show all	446 aa 48.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.