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CRIPAK

GENERAL INFORMATION

Gene name

 CRIPAK

Gene description

 Cysteine-rich PAK1 inhibitor

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CRIPAK (HGNC Symbol)

Synonyms

 FLJ34443

Description

 Cysteine-rich PAK1 inhibitor (HGNC Symbol)

Entrez gene summary

 CRIPAK is a negative regulator of PAK1 (MIM 602590) that is upregulated by estrogen (Talukder et al., 2006 [PubMed 16278681]).[supplied by OMIM, Mar 2008]

Chromosome

 4

Cytoband

 p16.3

Chromosome location (bp)

 1391552 - 1395989

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179979 (version 83.38)

Entrez gene

 285464

UniProt

 Q8N1N5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N1N5

Antibodypedia

 CRIPAK antibodies

PROTEIN BROWSER
CRIPAK-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CRIPAK-001
ENSP00000323978
ENST00000324803
Q8N1N5 [Direct mapping]
Cysteine-rich PAK1 inhibitor
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005783 [endoplasmic reticulum]
GO:0005886 [plasma membrane]
GO:0006469 [negative regulation of protein kinase activity]
GO:0033147 [negative regulation of intracellular estrogen receptor signaling pathway]
GO:0043627 [response to estrogen]
GO:0051493 [regulation of cytoskeleton organization]
Show all
 446 aa
48.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.