Expression of PITPNB in cancer - Summary

CANCER ATLAS

Gene description

Phosphatidylinositol transfer protein, beta

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Head and neck cancer

STAINING SUMMARY

HPA000528

GENE INFORMATION
Gene name	PITPNB (HGNC Symbol)
Synonyms	VIB1B
Description	Phosphatidylinositol transfer protein, beta (HGNC Symbol)
Entrez gene summary	This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	22
Cytoband	q12.1
Chromosome location (bp)	27851669 - 27920134
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180957 (version 83.38)
Entrez gene	23760
UniProt	P48739 (UniProt - Evidence at protein level)
neXtProt	NX_P48739
Antibodypedia	PITPNB antibodies

PROTEIN BROWSER

PITPNB-001	PITPNB-002	PITPNB-003	PITPNB-006	PITPNB-012	PITPNB-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PITPNB-001 ENSP00000334738 ENST00000335272	P48739 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0015914 [phospholipid transport] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0070062 [extracellular exosome] Show all	271 aa 31.5 kDa	No	0
PITPNB-002 ENSP00000321266 ENST00000320996	P48739 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0001701 [in utero embryonic development] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0015914 [phospholipid transport] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0070062 [extracellular exosome] Show all	272 aa 31.6 kDa	No	0
PITPNB-003 ENSP00000406542 ENST00000415296	B3KYB6 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	120 aa 13.8 kDa	No	0
PITPNB-006 ENSP00000403675 ENST00000436663	B3KYB7 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	168 aa 19.2 kDa	No	0
PITPNB-012 ENSP00000487693 ENST00000634017	P48739 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0005622 [intracellular] GO:0005789 [endoplasmic reticulum membrane] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0015914 [phospholipid transport] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0070062 [extracellular exosome] Show all	273 aa 31.7 kDa	No	0
PITPNB-201 ENSP00000405179 ENST00000455418	A0A0A0MSW4 [Direct mapping] Phosphatidylinositol transfer protein beta isoform Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0006810 [transport] Show all	271 aa 31.6 kDa	No	0