Expression of SLC25A42 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 25, member 42

Protein class

Predicted membrane proteins, Transporters

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049449

GENE INFORMATION
Gene name	SLC25A42 (HGNC Symbol)
Synonyms	MGC26694
Description	Solute carrier family 25, member 42 (HGNC Symbol)
Entrez gene summary	This gene encodes a solute carrier family 25 protein. Solute carrier family 25 proteins are localized to mitochondria and play critical roles in the transport of molecules across the inner mitochondrial membrane. The encoded protein is a mitochondrial transporter for coenzyme A (CoA) and adenosine 3',5'-diphosphate. [provided by RefSeq, Feb 2012]
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	19063999 - 19112888
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000181035 (version 83.38)
Entrez gene	284439
UniProt	Q86VD7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86VD7
Antibodypedia	SLC25A42 antibodies

PROTEIN BROWSER

SLC25A42-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC25A42-001 ENSP00000326693 ENST00000318596	Q86VD7 [Direct mapping] Mitochondrial coenzyme A transporter SLC25A42 A0A024R7K2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005347 [ATP transmembrane transporter activity] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0015217 [ADP transmembrane transporter activity] GO:0015228 [coenzyme A transmembrane transporter activity] GO:0015866 [ADP transport] GO:0015867 [ATP transport] GO:0016021 [integral component of membrane] GO:0035349 [coenzyme A transmembrane transport] GO:0043262 [adenosine-diphosphatase activity] GO:0080121 [AMP transport] GO:0080122 [AMP transmembrane transporter activity] Show all	318 aa 35.4 kDa	No	3